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pentobarbital will reduce the level or effect of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Could produce loss of virologic response and d